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Althea (Vernee Watson) was a character featured in both pilots and the first series episode.and Iris Bahr as Gilda, a scientist colleague and friend of the male characters.

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By coincidence, Robertson had recently read Simon Singh's book Big Bang, Lorre and Prady phoned him shortly thereafter and asked him to write the theme song.

Having been asked to write songs for other films and shows, but ending up being rejected because producers favored songs by other artists, Robertson agreed to write the theme only after learning that Lorre and Prady had not asked anyone else.

In September 2015, TMZ uncovered court documents showing that Steven Page sued former bandmate Robertson over the song, alleging that he was promised 20% of the proceeds, but that Robertson has kept that money entirely for himself.

For the first three seasons, Galecki, Parsons, and Cuoco, the three main stars of the show, received at most $60,000 per episode.

Over time, supporting characters have been promoted to starring roles: Leslie Winkle, a physicist who dated Leonard and Howard; neuroscientist Amy Farrah Fowler, who joins the group after being matched to Sheldon on a dating website (and later becomes Sheldon's girlfriend and fiancée); Bernadette Rostenkowski, Howard's wife (previously his girlfriend), a microbiologist and former part-time waitress alongside Penny; Stuart Bloom, the cash-strapped owner of the comic book store the characters often visit; and Emily Sweeney, a dermatologist who dated Raj.

The show's pilot episode premiered on September 24, 2007. A different pilot was produced for the 2006–07 television season but never aired.

By the end of April, Bialik and Rauch had signed deals to earn 0,000 per episode, each, with the deals also including a separate development component for both actors.

The deal was an increase from the 5,000 – 0,000 the duo had been making per episode. First row from left: Rajesh Koothrappali, Leonard Hofstadter, Penny, Sheldon Cooper, and Howard Wolowitz, second row from left: Bernadette Rostenkowski-Wolowitz and Amy Farrah Fowler As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show.

The Big Bang Theory is an American television sitcom created by Chuck Lorre and Bill Prady, both of whom serve as executive producers on the series, along with Steven Molaro. The geekiness and intellect of the four men are contrasted for comic effect with Penny's social skills and common sense.

The show is primarily centered on five characters living in Pasadena, California: Leonard Hofstadter and Sheldon Cooper, both physicists at Caltech, who share an apartment; Penny, a waitress and aspiring actress who later becomes a pharmaceutical representative and who lives across the hall; and Leonard and Sheldon's similarly geeky and socially awkward friends and co-workers, aerospace engineer Howard Wolowitz and astrophysicist Raj Koothrappali.

Famous astrophysicist and Nobel laureate George Smoot had a cameo appearance in the second season.

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